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Third, blood sugar regulation improves

BG-CPY was unable to specifically label GLP1R SNAP/SNAP islets, showing equivalent staining in GLP1R WT/WT islets (Fig

Over weeks and months, this naturally leads to a meaningful calorie deficit without the psychological suffering of traditional dieting

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Given that both T1DM and T2DM are associated with reduced beta-cell mass and function, these various studies highlight the therapeutic potential of harnessing alpha-cell GLP-1 production to not only stimulate insulin secretion but also promote beta-cell survival and regeneration

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