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If you're on semaglutide, tirzepatide, or considering GLP-1 therapy, establishing baseline liver enzymes and tracking changes gives you actionable data

"As we start to age, our bones are going to be weaker and we're going to lose muscle mass, which is going to increase your risk for things such as osteoporosis and even falls," said Shepherd, the author of "Generation M: Living Well in Perimenopause and Menopause." "With diet, you significantly want to increase your protein intake, and [with] exercise, changing those regimens to more of resistance training and weightlifting."

The authors declare no other competing interests

Most programs exclude people on Medicare or Medicaid due to federal regulations, and the discount typically applies only to brand-name medications purchased at participating pharmacies.

However, dedicated kidney outcome trials for GLP-1 receptor agonists remain limited, and further long-term studies are needed to better define their role in CKD management

The best recommendation is to have a washout period between taking GLP-1 agonists and getting pregnant