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Tirzepatide can help counterbalance these metabolic disruptions by reducing appetite and improving the bodys hormonal response to food

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The definition of weight maintenance

Add-on to metformin SURPASS-2 (NCT03987919) was a 40-week open-label trial (double-blind with respect to MOUNJARO dose assignment) that randomized 1879 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin alone to the addition of MOUNJARO 5 mg, MOUNJARO 10 mg, or MOUNJARO 15 mg once weekly or subcutaneous semaglutide 1 mg once weekly

Orforglipron was shown in a recent study to help patients lose 12.4% of their body weight

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