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Moreover, emerging research suggests that targeting both the GLP-1 and GIP pathways may lead to synergistic effects on body weight, glucose control, and cardiovascular health

A phase 2, adaptive randomized, double-blind, placebo-controlled, multicenter, 52-week study of HM15211 in patients with biopsy-confirmed non-alcoholic steatohepatitis - Study design and rationale of HM-TRIA-201 study

For weight management , non-pharmacological approaches are strongly recommended: Dietary modification : Working with a registered dietitian to develop a balanced eating plan that maintains adequate nutrition for milk production Physical activity : Gradual return to exercise as appropriate postpartum Behavioural support : Structured weight management programmes that address lifestyle factors Breastfeeding itself supports metabolic health and gradual postpartum weight loss

Limit greasy, heavy, or spicy foods

Forest plot of Albiglutide versus comparators on the risk of overall Respiratory diseases

Similarly, GLP-1R agonism induces cell proliferation and attenuates glucolipotoxicity through AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling [24]