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Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

Large clinical trials of GLP1 medicines, such as Ozempic and Wegovy, have shown benefits on heart health beyond weight loss

10.1245/s10434-008-0270-y 13 BollettaA.di TarantoG.LoscoL.EliaR.SertG.RibuffoD.et al (2022)

Some in-person weight loss programs, especially those through hospitals, offer discounts or income-based pricing

Pre- and perioperative glucocorticoids in high doses also potentially increase the risk for excessive weight gain
