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Participants who took Semaglutide lost 15% of their body weight on average, while those who took liraglutide lost around 6%
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(24) Additionally, a narrative review by Herrou et al
Discontinuation rates in TRIUMPH-4 12.2% of participants on 9mg and 18.2% on 12mg discontinued treatment, notably higher than Phase 2 rates
(Off label use of FDA compounds is not on unusual but typically its a doctor making those decisions not the patient)
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