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Contact your healthcare provider immediately if you experience severe persistent abdominal pain, inability to pass gas or have bowel movements, persistent vomiting, blood in stool, fever with gastrointestinal symptoms, or signs of dehydration

Many stimulants have potency at the rat TAAR1 in the micromolar range but tend to be about 5 to 10 times less potent at the human TAAR1, but bupropion was found to be inactive.87,88 "In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1" (PDF)

Appetite Regulation: The delay in gastric emptying also has an impact on appetite signals, which are partly regulated by how quickly the stomach empties its contents

Severe heartburn may be manageable with dietary changes, antacids, or dose adjustments