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Glucagon-like peptide-1: a key regulator of innate immune function with clinical efficacy in a range of inflammatory diseases

Fiocruz-EMSs tech transfer stands as the first large-scale domestic biosimilar effort, aiming to undercut branded prices by up to 40%

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Regulatory approvals for next-generation molecules are expected to stimulate additional opportunities across therapeutic applications

Nevertheless, some studies suggest that Ex-4 significantly stimulates hMSC proliferation in a dose- and time-dependent-manner, particularly at concentrations between 10 nM and 100 nM, as shown in cell viability assays 3-(4,5-dimethylthiazol-2-yl)5-(3-carboxymethoxyphenyl)2-(4-sulfophenyl)2 H-tetrazolium (MTS) and Cell Counting Kit-8 (CCK-8), as well as DNA analysis 5-ethynyl-2-deoxyuridin (EdU) incorporation and PicoGreen assay [14,15,16]