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This multifaceted mechanism is being actively studied for its ability toenhance metabolic function,reduce body weight, andimprove insulin sensitivitymore effectively than single or dual agonists

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While various medications have been known to cause muscle aches, Glucagon-like peptide 1 (GLP-1) agonists have not been commonly associated with this side effect in medical literature.GLP-1 agonists, such as tirzepatide and semaglutide, are highly effective in promoting weight loss

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Given these considerations, the therapeutic approach in older patients with T2D is complex, particularly in those who have functional dependence, frailty, dementia, or who are at end-of-life