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The UKs MHRA recently issued guidance reminding patients using the GLP-1 agonist tirzepatide, who are also on oral contraceptives, that a barrier form of contraception should also be used.

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Combined therapy with two classes of antidiabetic agents, namely, dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors, target several pathophysiological pathways