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INDICATION AND LIMITATIONS OF USE BYDUREON BCise is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus Not recommended as first-line therapy for patients inadequately controlled on diet and exercise Not indicated to treat type 1 diabetes Do not coadminister with other exenatide-containing products Not studied in patients with a history of pancreatitis

This means they have to be stable, they have to last longer without breaking down

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