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Weight regain after stopping: Both drugs: Expect to regain about 2/3 of lost weight within a year No significant difference between the two Neither drug is a permanent solution

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T2DM is a common comorbidity of CP with a point prevalence of approximately 3040% [17]

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injections of 100 nmol kg 1 MK-801 ( n = 8 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) at a volume of 5 l g 1

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