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25 Thus, GLP-1 could help to slow the progression of AD

It may be important to consider the role of dopaminergic signaling in feeding behavior in the context of GLP-1, as individuals with obesity have been found to have decreased D2R expression in striatal regions that project to the LH, suggesting that obesity may lead to decreased satiability and increased hyperphagia through this circuit [128]

When paired with your clinical history and metabolic biomarkers, a Precision Peptide Genetic Test result can support a more personalized medication selection conversation with your provider

But "tend to" is not a guarantee

Participants and investigators will remain blinded to treatment assignment throughout the trial period (main and extension phases)

Starting with medication does not close the door to surgery