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PMID: 28959180
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For many patients with obesity-related osteoarthritis, daily movement can feel like walking with a heavy backpack that never comes off
I suspect this improvement is multifactorial because diabetic patients feel better overall once their blood sugar is more adequately controlled, and obese patients find improved musculoskeletal symptoms and body image thoughts as they lose weight on these medications
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This layered approachstarting with appropriate dosing, monitoring thyroid labs closely, and refining therapy based on genetic datamaximizes safety and efficacy for complex cases
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If there is scar tissue / fibrosis, those will be clearly seen and you can differentiate between fibrosis, water retention or unremoved fat after all types of cosmetic surgery or harsh non-surgical procedures such as RF microneedling, extreme intensity HIFU etc
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10.1016/S0140-6736(14)60649-8 52 LeeP
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