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The aim of the present review is to examine the cellular processes underlying the actions of these new, highly significant classes of peptide receptor agonists

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Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

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However, there was no significant difference in adverse CVEs or all-cause mortality when compared with those taking SGLT2 inhibitors

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Thirteen trials involving 5,807 participants were identified

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GLP-1R agonists and perioperative outcomes 1

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