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Semaglutide is a versatile medication with multiple beneficial effects

It emphasizes how structural refinements and biochemical modifications can extend the application of GLP-1R agonists from the treatment of T2D to obesity ( Figure 3 2.3 Methods to Extend GLP-1s Half-Life The short action profile of native GLP-1 imposes a major challenge towards its successful clinical utilization

Initial evidence has come from studies in patients with type 2 diabetes, where agents like liraglutide and semaglutide have not only improved glycemic control but also been associated with reductions in depressive symptoms [63,64,69]

Furusawa S, Nomoto H, Yokoyama H, Suzuki Y, Tsuzuki A, Takahashi K, Miya A, Kameda H, Cho KY, Takeuchi J, Nagai S, Taneda S, Kurihara Y, Nakamura A, Atsumi T

These may indicate inadequate diabetes control requiring treatment modification

I also take another teaspoon of Metamucil in water later in the day if I have a sweet craving