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Alternative weight management therapies including other prescription medications, lifestyle modification programs, or surgical options where appropriate

In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)

Thyroid disease: Having an overactive thyroid gland can cause an irregular heartbeat

In TRIUMPH-4, it affected 8.8% of the 9mg group and 20.9% of the 12mg group, compared to just 0.7% on placebo

AstraZeneca PLC AstraZeneca is strengthening its portfolio with GLP-1 targeted drugs and actively engaging in clinical trials for obesity-related metabolic conditions

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