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The TRIUMPH-4 trial revealed a notable incidence of dysesthesia, an abnormal sensation affecting touch perception that can cause numbness, tingling, or unusual skin sensitivity

These medications work by mimicking the action of naturally occurring incretin hormones, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

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Its normal to experience some changes, such as nausea, especially during the first few weeks

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