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Cell culture studies have demonstrated that exenatide elevates endogenous TH levels in primary DAergic neurons, 35 leading to the augmentation of the phenotype under resting conditions

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Nature 630 , 9941002 (2024)

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The medication changes appetite regulation, and that change drives the reduction in calories

HR: 0.44, 95% CI: 0.380.52) and naltrexone or topiramate ( n = 715
