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Canada is the only country where Novo Nordisk allowed the patent for its semaglutide drugs to expire, paving the way for "regulatory exclusivity" to end on Jan

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Patients should contact their healthcare provider promptly if they develop jaundice yellowing of the skin or whites of the eyeswhich may indicate significant liver dysfunction or bile duct obstruction

[DOI] [PubMed] [Google Scholar] 137.Li CJ, Li J, Zhang QM, Lv L, Chen R, Lv CF, Yu P, Yu DM

doi: 10.1210/jc.2010-1290

They may also adjust the dosage if needed
