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A phase 3 study (NCT04822181), which enrolled 1200 patients with biopsy-proven MASH and fibrosis, is currently ongoing to assess the benefit of OW subcutaneous semaglutide 2 mg in this setting 93

Inhibition of GPR43/GPR109a expression by RNA interference Human G-protein-coupled receptor 43 (GPR43) or GPR109a siRNA or negative control (NC) siRNA was mixed with the Lipofectamine 2000 transfection reagent (Invitrogen, California, USA) (Table S1)

Certain agents (liraglutide, injectable semaglutide, dulaglutide) have demonstrated cardiovascular benefits in high-risk patients with type 2 diabetes

Design of the combinatioN effect of finerenone and empagliflozin in participants with chronic kidney disease and type 2 diabetes using a UACR endpoint study (CONFIDENCE)

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