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My joints were aching

Many people do, but combining medications changes the side-effect picture and blood sugar patterns in ways that vary by person

Theres no single answer, it depends on your goals and progress

The phase III SURMOUNT-3 trial by Thomas et al207 evaluated tirzepatide use following intensive lifestyle interventions

The REWIND trial included patients with hemoglobin A1c levels of up to 9.5%, thus the influence of dulaglutide on glycemic control may underlie the reduced risk of cognitive dysfunction

In fact, more than 30% of North American patients with RA also carry obesity, and this group tends to cycle through more medications before finding relief
