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So, even when compounded semaglutide contains the same active ingredient as Ozempic, semaglutide base, and is prepared by a state-licensed compounding pharmacy, we cannot say that it is as effective as Ozempic or Wegovy simply because it has not been studied and gone through FDA approval process

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As a result, the half-life was extended to 1516 days (compared to the one-week duration of analogs like semaglutide or tirzepatide) while maintaining equivalent potency, opening the door for once-monthly instead of weekly administration

Endocrine (2017) 58(1):14352