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Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing pioglitazone therapy in patients with type 2 diabetes: a 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

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Addition of LINA to EMPA enhances USE via reduction of ENaC expression, reduces UAE, and inhibits kidney injury in deoxycorticosterone acetate/salt (DS)-administered, uninephrectomized mice DS-administered, uninephrectomized mice (DS mice) have been known to exhibit glomerular hyperfiltration and severe kidney injury with ENaC activation 24

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