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Description
Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

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Type 2 diabetes mellitus (T2DM) is a complex chronic disease characterized by progressive -cell dysfunction and insulin resistance

These revealed similar peptide binding modes to that previously observed for GLP-1

2016;24:195561
Cryo-EM analysis of a complex involving an exendin-4 analogue, the GLP-1R and Gs protein revealed two receptor conformers with distinct modes of peptide-receptor engagement
