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Description
In this paper, the authors describe the energy state-dependent regulation of the PVNGLP-1R to DVC circuit, resulting in altered food intake and metabolic health, mediated by GLP-1 receptor signalling.
Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells that modulates glucose metabolism by controlling insulin excretion and glucagon secretion and inhibits gastric emptying leading to decreased food intake, thus limiting weight gain

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Plasma insulin and GLP-1 levels were compared with those of the water-administered controls

The undeniable impact of GLP-1 agonists on global health and nutrition left no seat unclaimed, as the only appetite left unsuppressed was for clarity on how the drug will shape the nutraceuticals industry.
