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As all of these endpoints were exploratory in nature, the P values were not adjusted for multiplicity

This location offers the most stable temperature because it is farthest from the door (which experiences temperature swings every time you open it) and away from both the cooling element (which can create localized freezing) and the bottom (where condensation collects)

Tirzepatide common side effects include nausea, vomiting, diarrhea, decreased appetite, constipation, and upset stomach

Some patients require a treatment break to allow symptoms to resolve

This physician-reviewed guide covers the most common first-week side effects, a day-by-day timeline, practical ways to feel better, and when to contact your healthcare provider

If you are still at 2.5mg or 5mg, escalation according to the schedule may be the answer