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Several lymphangiogenesis- and LNM-related growth factors have been characterized to date, including fibroblast growth factor (FGF)-2, which can bind FGFR3 on the surface of LECs to promote the development of lymphatic vessels

54 In unhealthy conditions, including those caused by a high-calorie, nutrient-poor diet, low-level inflammation causes fat cells to become increasingly resistant to the effects of insulin

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