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Acknowledgments This work was supported by the Ministerium fr Wissenschaft und Forschung des Landes Nordrhein-Westfalen (Ministry of Science and Research of the State of North Rhine-Westphalia), and the Bundesministerium fr Gesundheit (Federal Ministry of Health)

doi: 10.2337/dc12-2006

However, some people are more severely affected and cannot continue treatment (Shiomi et al., 2019)

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