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Increase in chemokine CXCL1 by ER ligand treatment is a key mediator in promoting axon myelination
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In individuals with T2D, epigenetic modifications, specifically increased DNA methylation of the GLP-1R gene, reduce receptor expression, impairing the function of GLP-1 and lowering insulin secretion
yet the consequences of the expression of these receptors and comparisons with nonthyroid cancer cells in humans require further evaluation

Association of semaglutide with tobacco use disorder in patients with type 2 diabetes: Target trial emulation using real-world data