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Unfortunately, such a clinical trial has not yet been performed

In the placebo group
Carolean is a natural fibre complex made from carob and cactus (Opuntia), designed to support both satiation and satiety the two key signals that help regulate appetite

Lee SW, Gregory D, Cool CL

In the pancreas, they enhance glucose-dependent insulin secretion and suppress glucagon release, improving blood sugar control with a low risk of hypoglycemia when used alone (though risk increases when combined with insulin or sulfonylureas)

To do this merely manufacturing wont suffice
