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Patients were matched in a 1:1 ratio using the nearest neighbor matching algorithm, with a caliper width of 0.2 standard deviations of the logit of the propensity score

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Avoid injecting the night before a day where migraines would be particularly disruptive, like an important work presentation or a long drive

Providing research participants with increased ownership and decision making when it comes to choosing which studies they would like to participate in, instead of relying on study sites to make these decisions, can be another means to improve clinical trial recruitment and potentially the diversity of participants (Smith, 2024)

Metformin, a prescription diabetes drug in the sulfonylureas class, is typically the first-line treatment for Type 2 diabetics and has also been linked to weight loss, though it is not approved for it

Especially regarding the central nervous system, the expression of GLP-1 receptors in reward-related regions, such as the hypothalamus, amygdala, nucleus accumbens, paraventricular nucleus, ventral tegmental area, locus coeruleus, and brain stem [21] may suggest a possible association between reward learning and symptoms like anhedonia in diseases such as depression