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This timeline can act as a general guide as your body adjusts to the medication

This contrasts with compounded GLP-1 options, which are prepared by 503A compounding pharmacies under different regulatory oversight

In one such study, 68 weeks in duration, people given semaglutide injections lost an average of 15-20% of their total body weight

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Novo first reported in 2023 that the drug, an oral form of semaglutide, succeeded in a Phase 3 trial, helping people on the highest dose lose about 15% of their body weight after 64 weeks