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The consequences of these maladaptive changes are increase in myocardial stiffness and reduced ventricular compliance which play a vital role in the development of LV diastolic dysfunction leading to heart failure with preserved ejection fraction (HFpEF), the most common form of HF in T2DM (40)

Others explore microdosing tirzepatide as a maintenance strategy after reaching their target weight

No exercise or diet required, fat-burning targeted therapy

Ozer discusses new #GLP1 medications to help lower blood sugar

GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda)along with tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, have transformed the management of type 2 diabetes and obesity

While all GLP-1 agonists share some common gastrointestinal effects, the triple agonism of retatrutide introduces glucagon receptor-mediated effects that the others do not produce