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A 2014 FDA and European Medicines Agency (EMA) joint analysis found similar rates of pancreatic cancer between GLP-1-treated patients and comparators, though absolute event numbers were small

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Lebrun LJ, Lenaerts K, Kiers D, et al

They also increase plasma erythropoietin levels, thereby increasing haematocrit and improving cardiac output [110, 111]

In an ideal setting, weight loss achieved with GLP-1 agonist therapy in the short-term could be durable without pharmacotherapy for many years and perhaps over a lifetime