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Description

Hyaluronic acid (HA) is a naturally occurring compound found throughout the bodyespecially in the skinwhere it helps attract and hold onto moisture

Methods This is a cohort study combining several population-wide databases and covering a Spanish population of five million inhabitants, including all adults with obesity who initiated treatment with either GLP-1RA or SGLT-2i for type 2 diabetes from 2015 to 2021

Over 18 months, the condition occurred in approximately 8 cases per 10,000 GLP-1 users, compared with 4 to 6 cases among comparison groups

Watch for new or worsening depression, suicidal thoughts, or unusual behavioral mood changes

Novo Nordisk has highlighted strong early uptake for its obesity pill in the US in early 2026 , framing oral semaglutide in obesity as part of its growth strategy beyond injectables