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The mean differences in A1c and body weight between IDegLira and basalbolus therapy and IDeglira and basal glargine were 0.3% and 6.89 kg and 0.65% and 4.04 kg respectively

12-14 Exenatide is available in pen form, potentially making dosing and administration more convenient ( TABLE 1 )

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In Phase II trials: Efinopegdutide (Merck/Johnson & Johnson/Hanmi Harma), VK2735 (Viking Therapeutics), BGM0504 (BrightGene), Pemvidutide (Altimmune/Spitfire Pharma), AMG133 (Amgen), Dapiglutide (Zealand Pharma), etc

These therapies work by increasing insulin secretion, slowing gastric emptying, and reducing appetite

Inflammation Attenuating Effects Evidence suggests that inflammation in organs such as the liver, kidneys, and heart can be reduced by GLP-1R agonists [48]