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Treatment with 30 g/kg AC3174, an exenatide analog, administered via an osmotic pump for 28 days in Lep ob mice on a high trans -fat diet significantly reduced liver weight, hepatic lipid accumulation, and plasma alanine transaminase levels in comparison with pair-fed, weight-matched controls (30)
GLP-1RAs demonstrate preventive and therapeutic potential in pancreatic cancer, hepatic cancer and CRC, require caution in MTC, and exhibit paradoxical effects in breast cancer and EC
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Kim KH, Lee IS, Park JY, Kim Y, An EJ, Jang HJ
This primes your satiety hormones to start working before you move on to the starchier parts of the meal
Higher doses tend to bring more noticeable side effects than starter doses
