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In summary, GLP-1 receptor agonists regulate hepatic lipid metabolism in MASLD through activation of AMPK-mediated fatty acid -oxidation, suppressing lipogenesis-related gene expression, and enhancing lipid export and autophagy

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doi: 10.3389/fcvm.2024.1379189 Received 30 January 2024 Accepted 21 June 2024 Published 05 July 2024 Volume 11 - 2024 Edited by Sonia Eiras, Health Research Institute of Santiago de Compostela (IDIS), Spain Reviewed by Abhinav Grover, Medical College of Wisconsin, United States Federica Fogacci, University of Bologna, Italy Angelo Maria Patti, University of Palermo, Italy Updates Copyright 2024 Masson, Lobo, Nogueira, Rodriguez-Granillo, Barbagelata and Siniawski