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Description
Notably, the US FDA submission documents for tirzepatide include predictions of DDIs mediated by delayed gastric emptying using PBPK modeling, rather than conducting clinical DDI studies for certain drugs (Table 6).58 PBPK modeling is a mathematical approach that uses differential equations to predict pharmacokinetics in humans and other species
Crohns Colitis 17 , 12071216 (2023)
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