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Description
A further study conducted on IBD patients and not diagnosed with DM2 also reported no significant alterations in inflammatory markers

Moderate adverse effects include dizziness, mild increased heart rate, infections, headaches, and indigestion

Marsha Novick: Mild nausea, constipation, diarrhea, fatigue, and low appetite are fairly common with GLP-1 medications like semaglutide (Wegovy) and tirzepatide (Zepbound), especially in the first few days after an injection or after a dose increase

FDA drug safety communication

A study in rats (Ramrez et al., 2018) has showed that the DPP4 inhibitor sitagliptin induces a lowering of fatty acid utilization in cardiomyocytes in favour of glucose

Patients receiving semaglutide (0.5 or 1.0 mg) for 104 weeks demonstrated a significantly higher risk of diabetic retinopathy complications, including vitreous hemorrhage, blindness, or required procedural treatment compared to those receiving placebo (HR, 1.76
