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10.1007/s00429-020-02167-7 Brain Struct Funct

Conclusions This growing body of evidence suggests that GLP-1 analogs could influence the gut microbiome in ways that support long-term metabolic and intestinal health

2,3 Regarding diuretics, the population-based study by Yadav et al found an odds ratio of 1.6 (95% confidence interval 1.22.1) for the development of CI with diuretic use in the 30 days before CI

Your treatment duration depends on factors such as your overall health, weight loss goals, and response to the medication

Topiramate has similar benefits for weight reduction in psychiatric patients, but cognitive impairment limits its usage (McIntyre RS et al, Am J Psychiatry 2024;181(1):2638)

Last reviewed: June 15, 2026 Last updated: June 15, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations