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Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma

The Bottom Line May 2026 Status Compounded semaglutide remains legal in May 2026 through 503A patient-specific compounding when prepared by licensed pharmacies under valid prescriptions with documented clinical rationale

OZEMPIC injection is available as multiple-dose pre-filled pens for single-patient use, designed for once-weekly dosing

Throat Culture Follow-Up If the rapid test is negative but symptoms strongly suggest strep: A throat culture may be ordered Results take 2448 hours Provides higher sensitivity 3

Instructions tend to vary according to each venue

PRECIDENTD, PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes (NCT05390892)