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Some have to hold the current dose longer or reduce it for a while
Patients with certain FTO and MC4R variants often achieve superior results with dual-agonist therapy rather than single-compound approaches

Ongoing clinical trials are planned, including evaluating tirzepatide as adjunctive therapy in individuals with a BMI over 27 who are already receiving infliximab or adalimumab treatment (NCT06774079)

7 Future research should prioritize longitudinal studies to determine safety and effectiveness in diverse female populations

Howard, S

Roles of the vestibular system in obesity and impaired glucose metabolism in high-fat diet-fed mice
