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Patients may consider microdosing if they: Have a small amount of weight to lose Want help reducing food noise Are interested in weight maintenance Are sensitive to medication side effects Want a gradual introduction to GLP-1 therapy Flow Wellness works with patients to determine whether a lower-dose approach aligns with their goals

To achieve this, we estimated CV treatment effects by conducting a post hoc meta-analysis of data from SUSTAIN and PIONEER phase 3a trials, with subjects distributed across the continuum of baseline CV risk

In addition, longitudinal analyses confirm a progressive reduction in these effects with prolonged use and minimal discontinuation rates due to gastrointestinal intolerance (Hankosky et al., 2025