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Once the triggering stressor stabilizes, meaning weight loss slows and nutritional status is optimized, hair follicles resume their normal growth cycle

Developing strategies to modify basement membrane collagen levels, for example, by altering precise components of TGF-beta signalling, or collagenase activity 59,61,62,63 , could provide more efficient and specific therapeutic approaches

Like GLP-1s, mindfulness affects the brain's DMN

5 Future directions The potential of GLP-1RAs as dual-action therapies, targeting both metabolic dysfunction and immune dysregulation, makes them particularly compelling candidates for early PsA, where intervention may alter disease trajectory

Compounded GLP-1 medications are not FDA-approved or reviewed for safety, effectiveness, or quality

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