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But whats actually true about these GLP-1 drugs

Rapid Weight Loss and Skeletal Stress The most common explanation for joint pain during semaglutide therapy is metabolic stress from rapid weight loss

Studies have shown that stopping GLP-1 therapy often leads to weight regain [intermountainhealthcare.org], likely because the appetite returns to baseline

People have low body weight and lack insulin

Retatrutide is a triple agonist a peptide that binds to and activates three receptors, in the same way the body naturally would when functioning optimally

Any suspected adverse reactions should be reported through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)