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Clinical trials have demonstrated average weight loss of about 15% of initial body weight when combined with lifestyle modifications including reduced-calorie diet and increased physical activity, with some individuals achieving 20% weight loss

10.1177/10398562211010796 2 AmaroA.SugimotoD.WhartonS

Rotate sites with each dose

Epidemiological data are consistent in demonstrating that users of GLP-1RAs have reduced risk of developing PD, ranging from 25%50% risk reduction compared with users of other oral T2DM medications (138, 152, 153)

doi: 10.1371/journal.pone.0241338 15 ZhaoLChenYXiaFAbudukerimuBZhangWGuoYet al

60 Although modest at the individual level, a 5 mm Hg SBP reduction has been associated with about a 10% lower risk of major cardiovascular events, including 13% reductions in both stroke and heart failure, 8% in ischemic heart disease, and 5% in cardiovascular death, making these effects important at a population level
