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1 This concern emerged in Phase 3 and wasnt seen in Phase 2

GLP-1 effects on visceral illness Inhibition of food intake can be due to other factors than satiety, including gastric discomfort, e.g., gastroparesis, associated with visceral illness and stress

NHS Access Pending as Regulator Confirms Ongoing Safety Monitoring Although the tablet has been approved for use in the UK, it is not currently available on the NHS

[3] [4] The delayed gastric emptying effect varies in intensity among different agents and individual patients, with clinical implications that warrant careful consideration in practice

References: Charbonnel B, Cariou B (2011): Pharmacological management of type 2 diabetes: the potential of incretin-based therapies

glucose tolerance test (ipGTT) in C57BL/6J mice fasted overnight (16 h), p.o