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In a murine model of nephrotoxic serum nephritis, GLP-1R activation suppressed the proliferation of pro-inflammatory T helper 1 and T helper 17 cells, while reducing IL-6 production, thereby exerting renal protective effects (105)
Abbreviations: AMI: acute myocardial infarction
Ther Adv Musculoskelet Dis
We measured mRNA levels of GLP-1R, PC1/3, PC2 and Pdx1 in cells by PCR, and the trend was also consistent with the trend of their protein expression (Figures 5HK)
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Cardiovascular outcomes have been favorable
